Different on most bows.
Most manufactuers give you a strating center shot and knocking point for most the bows based on arrow centered with berger hole.
Some bows for me shoot and tune better close to risor shelf.
Elite bows, Vortex Binos, Trophy Taker sights, Carter releases, Goldtip Arrows. CBE sights, Vapor Trail Strings, B Stinger stabilizers